Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rpoERNA polymerase sigma-30 factor; Identified by similarity to SP:P34086; match to protein family HMM PF04542; match to protein family HMM PF04545; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)    
Predicted Functional Partners:
MCA1470
Conserved domain protein; Identified by similarity to GP:18496604.
  
 
 0.978
MCA1469
Putative sigma-E factor regulatory protein; Identified by similarity to SP:P46186.
 
 
 0.960
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.849
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.840
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.840
mucC
Sigma factor regulator MucC; Identified by similarity to GP:1345103; match to protein family HMM PF04246.
  
  
 0.801
MCA1246
Putative methyltransferase CheR; Identified by match to protein family HMM PF00563; match to protein family HMM PF00785; match to protein family HMM PF00990; match to protein family HMM PF01739; match to protein family HMM PF03705; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254.
    
 
 0.794
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.793
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
 
     0.788
MCA0829
Methyltransferase, CheR family; Identified by match to protein family HMM PF00515; match to protein family HMM PF01739; match to protein family HMM PF07719.
   
 
 0.738
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.