MCA1477 protein (Methylococcus capsulatus) - STRING interaction network

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Score

MCA1477

Conserved hypothetical protein TIGR00052; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052. (200 aa)

Predicted Functional Partners:

nnrD

0.908

pgm

0.902

prsA

0.900

MCA1716

0.900

MCA2782

0.900

MCA1478

0.773

cpdA

0.711

vacB

0.693

birA

0.643

rluC

0.609

Your Current Organism:

Methylococcus capsulatus

NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCA1477	MCA1478	MCA1477	MCA1478	Conserved hypothetical protein TIGR00052; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052.	Putative signal peptide peptidase SppA; Identified by similarity to SP:O34525; match to protein family HMM PF01343; match to protein family HMM TIGR00706.	0.773
MCA1477	MCA1716	MCA1477	MCA1716	Conserved hypothetical protein TIGR00052; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052.	In some systems, close homologs of ribose-phosphate pyrophosphokinase lacking enzymatic activity exist and perform regulatory functions; identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251.	0.900
MCA1477	MCA2782	MCA1477	MCA2782	Conserved hypothetical protein TIGR00052; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052.	Identified by similarity to GP:150994; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	0.900
MCA1477	birA	MCA1477	MCA1781	Conserved hypothetical protein TIGR00052; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052.	birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.	0.643
MCA1477	cpdA	MCA1477	MCA2085	Conserved hypothetical protein TIGR00052; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052.	Cyclic AMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.	0.711
MCA1477	nnrD	MCA1477	MCA1301	Conserved hypothetical protein TIGR00052; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052.	YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family.	0.908
MCA1477	pgm	MCA1477	MCA0607	Conserved hypothetical protein TIGR00052; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052.	Phosphoglucomutase; Identified by similarity to SP:P39671; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	0.902
MCA1477	prsA	MCA1477	MCA1056	Conserved hypothetical protein TIGR00052; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052.	Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.	0.900
MCA1477	rluC	MCA1477	MCA1479	Conserved hypothetical protein TIGR00052; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052.	Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.	0.609
MCA1477	vacB	MCA1477	MCA1976	Conserved hypothetical protein TIGR00052; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052.	Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.	0.693
MCA1478	MCA1477	MCA1478	MCA1477	Putative signal peptide peptidase SppA; Identified by similarity to SP:O34525; match to protein family HMM PF01343; match to protein family HMM TIGR00706.	Conserved hypothetical protein TIGR00052; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052.	0.773
MCA1478	rluC	MCA1478	MCA1479	Putative signal peptide peptidase SppA; Identified by similarity to SP:O34525; match to protein family HMM PF01343; match to protein family HMM TIGR00706.	Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.	0.624
MCA1716	MCA1477	MCA1716	MCA1477	In some systems, close homologs of ribose-phosphate pyrophosphokinase lacking enzymatic activity exist and perform regulatory functions; identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251.	Conserved hypothetical protein TIGR00052; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052.	0.900
MCA1716	MCA2782	MCA1716	MCA2782	In some systems, close homologs of ribose-phosphate pyrophosphokinase lacking enzymatic activity exist and perform regulatory functions; identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251.	Identified by similarity to GP:150994; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	0.918
MCA1716	pgm	MCA1716	MCA0607	In some systems, close homologs of ribose-phosphate pyrophosphokinase lacking enzymatic activity exist and perform regulatory functions; identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251.	Phosphoglucomutase; Identified by similarity to SP:P39671; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	0.903
MCA1716	prsA	MCA1716	MCA1056	In some systems, close homologs of ribose-phosphate pyrophosphokinase lacking enzymatic activity exist and perform regulatory functions; identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251.	Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.	0.925
MCA2782	MCA1477	MCA2782	MCA1477	Identified by similarity to GP:150994; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	Conserved hypothetical protein TIGR00052; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052.	0.900
MCA2782	MCA1716	MCA2782	MCA1716	Identified by similarity to GP:150994; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	In some systems, close homologs of ribose-phosphate pyrophosphokinase lacking enzymatic activity exist and perform regulatory functions; identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251.	0.918
MCA2782	pgm	MCA2782	MCA0607	Identified by similarity to GP:150994; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	Phosphoglucomutase; Identified by similarity to SP:P39671; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	0.940
MCA2782	prsA	MCA2782	MCA1056	Identified by similarity to GP:150994; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.	0.918

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