Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MCA1599Putative serine protease, MucD; Identified by similarity to GP:1345104; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037; Belongs to the peptidase S1C family. (504 aa)    
Predicted Functional Partners:
htrA
Protease DO; Identified by similarity to SP:P09376; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037; Belongs to the peptidase S1C family.
  
  
 
0.915
MCA1467
Serine protease, MucD; Identified by similarity to GP:1345104; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037; Belongs to the peptidase S1C family.
  
  
 
0.906
MCA1596
Multidrug efflux system, HlyD family subunit; Identified by similarity to OMNI:NTL03PA02493; match to protein family HMM PF00529; match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.596
MCA1597
Multidrug efflux transporter MexF; Identified by similarity to GP:1707645; match to protein family HMM PF00873; match to protein family HMM TIGR00915.
       0.596
MCA1598
Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440.
       0.596
MCA1470
Conserved domain protein; Identified by similarity to GP:18496604.
  
 
 0.589
MCA1595
Multidrug efflux system outer membrane subunit; Identified by similarity to GP:19716262; match to protein family HMM PF02321; match to protein family HMM TIGR01845.
 
     0.520
hypC
Hydrogenase assembly chaperone hypC/hupF; Identified by similarity to SP:P24191; match to protein family HMM PF01455; match to protein family HMM TIGR00074.
       0.510
hypA
Hydrogenase expression/formation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
       0.510
MCA2199
Ankyrin repeat domain protein; Identified by match to protein family HMM PF00023.
  
 0.470
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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