Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
bolAbolA protein; Identified by similarity to SP:P15298; match to protein family HMM PF01722; Belongs to the BolA/IbaG family. (95 aa)    
Predicted Functional Partners:
MCA2078
Glutaredoxin-related protein; Identified by similarity to GP:19880969; match to protein family HMM PF00462; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 
 0.938
MCA0259
Glutaredoxin-related protein; Identified by similarity to GP:19880969; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 
 0.932
ispZ
Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
  
    0.832
MCA1643
Peptidyl-prolyl cis-trans isomerase family protein; Identified by match to protein family HMM PF00639.
  
    0.818
MCA1645
Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA03202; match to protein family HMM PF03795.
       0.818
nifA
Transcriptional regulator NifA; Identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM TIGR01199; match to protein family HMM TIGR01817.
      
 0.647
hscA
Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
    
 
 0.625
dnaK
dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 
 0.625
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
      
 0.623
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
      
 0.622
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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