Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA1663Identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377; Belongs to the anti-sigma-factor antagonist family. (108 aa)    
Predicted Functional Partners:
MCA1666
Sensor histidine kinase; Identified by match to protein family HMM PF02518.
 
 
 0.980
MCA1685
Anti-sigma B factor; Identified by similarity to SP:P17904; match to protein family HMM PF02518.
 
 
 0.955
MCA2750
HAMP domain protein; Identified by match to protein family HMM PF00672; match to protein family HMM PF07228.
 
 
 0.885
MCA1683
Sensory box protein; Identified by match to protein family HMM PF00785; match to protein family HMM PF00989; match to protein family HMM PF07228; match to protein family HMM TIGR00229.
 
 
 0.797
MCA1440
Response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF07228.
 
 
 0.781
MCA1204
Sensory box histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00785; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM TIGR00229.
 
  
 0.756
MCA1664
Identified by match to protein family HMM PF00860.
 
     0.748
MCA0833
Response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF07228.
 
 
 0.724
MCA1665
Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
 
     0.697
MCA1662
Putative ligand binding protein.
       0.661
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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