| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCA0309 | bfr-1 | MCA0309 | MCA0762 | Conserved hypothetical protein; Identified by similarity to GP:9950618; match to protein family HMM PF01243. | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | 0.900 |
| MCA0309 | bfr-2 | MCA0309 | MCA1369 | Conserved hypothetical protein; Identified by similarity to GP:9950618; match to protein family HMM PF01243. | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | 0.900 |
| MCA0309 | cyoE | MCA0309 | MCA0062 | Conserved hypothetical protein; Identified by similarity to GP:9950618; match to protein family HMM PF01243. | Protoheme IX farnesyl transferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | 0.900 |
| MCA0309 | hemH | MCA0309 | MCA1671 | Conserved hypothetical protein; Identified by similarity to GP:9950618; match to protein family HMM PF01243. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.903 |
| MCA1258 | hemE | MCA1258 | MCA0332 | Conserved hypothetical protein TIGR00701; Identified by match to protein family HMM PF03653; match to protein family HMM TIGR00701. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.432 |
| MCA1258 | hemH | MCA1258 | MCA1671 | Conserved hypothetical protein TIGR00701; Identified by match to protein family HMM PF03653; match to protein family HMM TIGR00701. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.943 |
| bfr-1 | MCA0309 | MCA0762 | MCA0309 | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | Conserved hypothetical protein; Identified by similarity to GP:9950618; match to protein family HMM PF01243. | 0.900 |
| bfr-1 | bfr-2 | MCA0762 | MCA1369 | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | 0.905 |
| bfr-1 | hemH | MCA0762 | MCA1671 | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.909 |
| bfr-2 | MCA0309 | MCA1369 | MCA0309 | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | Conserved hypothetical protein; Identified by similarity to GP:9950618; match to protein family HMM PF01243. | 0.900 |
| bfr-2 | bfr-1 | MCA1369 | MCA0762 | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | 0.905 |
| bfr-2 | hemH | MCA1369 | MCA1671 | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.909 |
| cyoE | MCA0309 | MCA0062 | MCA0309 | Protoheme IX farnesyl transferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | Conserved hypothetical protein; Identified by similarity to GP:9950618; match to protein family HMM PF01243. | 0.900 |
| cyoE | hemH | MCA0062 | MCA1671 | Protoheme IX farnesyl transferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.923 |
| dnaK | hemH | MCA1856 | MCA1671 | dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.704 |
| dusA | folE | MCA1669 | MCA1670 | TIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | GTP cyclohydrolase I; Identified by similarity to SP:Q54769; match to protein family HMM PF01227; match to protein family HMM TIGR00063. | 0.754 |
| dusA | hemH | MCA1669 | MCA1671 | TIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.721 |
| folE | dusA | MCA1670 | MCA1669 | GTP cyclohydrolase I; Identified by similarity to SP:Q54769; match to protein family HMM PF01227; match to protein family HMM TIGR00063. | TIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | 0.754 |
| folE | hemH | MCA1670 | MCA1671 | GTP cyclohydrolase I; Identified by similarity to SP:Q54769; match to protein family HMM PF01227; match to protein family HMM TIGR00063. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.821 |
| hemE | MCA1258 | MCA0332 | MCA1258 | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | Conserved hypothetical protein TIGR00701; Identified by match to protein family HMM PF03653; match to protein family HMM TIGR00701. | 0.432 |
