| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCA0629 | MCA1678 | MCA0629 | MCA1678 | Putative phosphomethylpyrimidine kinase; Identified by similarity to SP:P55882. | Putative nucleotide pyrophosphorylase; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586. | 0.911 |
| MCA0629 | MCA2211 | MCA0629 | MCA2211 | Putative phosphomethylpyrimidine kinase; Identified by similarity to SP:P55882. | Identified by match to protein family HMM PF00899; match to protein family HMM PF05237. | 0.798 |
| MCA0629 | MCA2715 | MCA0629 | MCA2715 | Putative phosphomethylpyrimidine kinase; Identified by similarity to SP:P55882. | Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01266; match to protein family HMM TIGR02352. | 0.443 |
| MCA0629 | birA | MCA0629 | MCA1781 | Putative phosphomethylpyrimidine kinase; Identified by similarity to SP:P55882. | birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.445 |
| MCA0629 | thiC | MCA0629 | MCA2710 | Putative phosphomethylpyrimidine kinase; Identified by similarity to SP:P55882. | Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.996 |
| MCA0629 | thiS | MCA0629 | MCA1077 | Putative phosphomethylpyrimidine kinase; Identified by similarity to SP:P55882. | Thiamine biosynthesis protein ThiS; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.991 |
| MCA1678 | MCA0629 | MCA1678 | MCA0629 | Putative nucleotide pyrophosphorylase; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586. | Putative phosphomethylpyrimidine kinase; Identified by similarity to SP:P55882. | 0.911 |
| MCA1678 | MCA2211 | MCA1678 | MCA2211 | Putative nucleotide pyrophosphorylase; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586. | Identified by match to protein family HMM PF00899; match to protein family HMM PF05237. | 0.671 |
| MCA1678 | MCA2715 | MCA1678 | MCA2715 | Putative nucleotide pyrophosphorylase; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586. | Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01266; match to protein family HMM TIGR02352. | 0.731 |
| MCA1678 | argJ | MCA1678 | MCA1679 | Putative nucleotide pyrophosphorylase; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586. | Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.751 |
| MCA1678 | birA | MCA1678 | MCA1781 | Putative nucleotide pyrophosphorylase; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586. | birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.763 |
| MCA1678 | nnrD | MCA1678 | MCA1301 | Putative nucleotide pyrophosphorylase; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586. | YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. | 0.807 |
| MCA1678 | ribBA | MCA1678 | MCA1656 | Putative nucleotide pyrophosphorylase; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.637 |
| MCA1678 | secA | MCA1678 | MCA1680 | Putative nucleotide pyrophosphorylase; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | 0.730 |
| MCA1678 | thiC | MCA1678 | MCA2710 | Putative nucleotide pyrophosphorylase; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586. | Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.880 |
| MCA1678 | thiS | MCA1678 | MCA1077 | Putative nucleotide pyrophosphorylase; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586. | Thiamine biosynthesis protein ThiS; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.985 |
| MCA2211 | MCA0629 | MCA2211 | MCA0629 | Identified by match to protein family HMM PF00899; match to protein family HMM PF05237. | Putative phosphomethylpyrimidine kinase; Identified by similarity to SP:P55882. | 0.798 |
| MCA2211 | MCA1678 | MCA2211 | MCA1678 | Identified by match to protein family HMM PF00899; match to protein family HMM PF05237. | Putative nucleotide pyrophosphorylase; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586. | 0.671 |
| MCA2211 | thiC | MCA2211 | MCA2710 | Identified by match to protein family HMM PF00899; match to protein family HMM PF05237. | Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.914 |
| MCA2211 | thiS | MCA2211 | MCA1077 | Identified by match to protein family HMM PF00899; match to protein family HMM PF05237. | Thiamine biosynthesis protein ThiS; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.996 |
