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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA1713Sigma-54 dependent DNA-binding response regulator; Identified by similarity to OMNI:NTL01ST2559; match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM TIGR01199. (460 aa)    
Predicted Functional Partners:
MCA1715
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
 
 
  0.988
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.953
MCA0831
Chemotaxis protein; Identified by similarity to SP:P18769; match to protein family HMM PF00072; match to protein family HMM PF01627; match to protein family HMM PF02518.
  
 
 0.757
MCA1714
Surface protein-related protein; Identified by similarity to GP:8996050.
       0.723
MCA1716
In some systems, close homologs of ribose-phosphate pyrophosphokinase lacking enzymatic activity exist and perform regulatory functions; identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251.
       0.645
MCA1717
Glycosyl transferase; Identified by match to protein family HMM PF00591; match to protein family HMM PF02885; match to protein family HMM PF07831.
       0.636
MCA1204
Sensory box histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00785; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM TIGR00229.
  
 
 0.628
ntrB
Nitrogen regulation protein NR(II); Identified by similarity to SP:P06712; match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM TIGR00229.
 
 0.550
MCA1712
Putative cysZ protein; Identified by similarity to SP:P12610; match to protein family HMM PF04401.
       0.541
MCA1246
Putative methyltransferase CheR; Identified by match to protein family HMM PF00563; match to protein family HMM PF00785; match to protein family HMM PF00990; match to protein family HMM PF01739; match to protein family HMM PF03705; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254.
  
 
 0.473
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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