Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pipProline iminopeptidase; Identified by similarity to SP:P52279; match to protein family HMM PF00561; match to protein family HMM TIGR01249; Belongs to the peptidase S33 family. (316 aa)    
Predicted Functional Partners:
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
    
  0.900
MCA1006
Acyltransferase family protein; Identified by similarity to OMNI:NTL01AA00691; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF01553.
  
 
 0.825
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
   
 
 0.677
MCA2107
Putative nonribosomal peptide synthetase; Identified by similarity to GP:9715733; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM TIGR01733; match to protein family HMM TIGR02353; Belongs to the ATP-dependent AMP-binding enzyme family.
 
   
 0.610
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
     
 0.591
MCA1738
Hypothetical protein; Identified by Glimmer2; putative.
       0.580
rfaE
Lipopolysaccharide biosynthesis protein RfaE; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family.
       0.563
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
       0.555
MCA1238
Polyketide synthase; Identified by similarity to GP:24575128; match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01590; match to protein family HMM PF02801.
 
 0.544
apaH
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
   
  0.425
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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