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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gabDSuccinate-semialdehyde dehydrogenase (NADP+); Identified by similarity to SP:P25526; match to protein family HMM PF00171; match to protein family HMM TIGR01780; Belongs to the aldehyde dehydrogenase family. (491 aa)    
Predicted Functional Partners:
sdhA
Succinate dehydrogenase, flavoprotein subunit; Identified by similarity to SP:P31038; match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM TIGR01812; match to protein family HMM TIGR01816; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
   
 0.948
sdhB
Succinate dehydrogenase, iron-sulfur protein; Identified by similarity to SP:Q59662; match to protein family HMM PF00111; match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
 0.947
gltA
Citrate synthase; Identified by similarity to SP:Q10530; match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family.
  
 0.926
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
    
 0.908
MCA1549
Putative succinate dehydrogenase, hydrophobic membrane anchor protein; Identified by similarity to SP:P10445; match to protein family HMM PF01127.
   
 
 0.907
MCA1548
Putative succinate dehydrogenase, cytochrome b556 subunit; Identified by similarity to SP:P10446; match to protein family HMM PF01127.
   
 
 0.906
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
    
 0.878
sucA
2-oxoglutarate dehydrogenase, E1 component; Identified by similarity to SP:P07015; match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239.
   
 
 0.878
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.868
MCA1132
Conserved hypothetical protein; Identified by similarity to GP:17131502.
  
 
 0.848
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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