close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA1778Cytochrome oxidase assembly protein; Identified by match to protein family HMM PF02628. (323 aa)    
Predicted Functional Partners:
cyoE
Protoheme IX farnesyl transferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 0.986
MCA0882
Putative cytochrome c oxidase assembly protein; Identified by similarity to SP:P56940; match to protein family HMM PF04442.
 
 0.959
MCA0131
Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA00111.
 
 
 0.856
MCA0132
Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA00112.
 
 
 0.689
MCA0879
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 
  
 0.653
MCA0883
Cytochrome c oxidase, subunit III; Identified by similarity to OMNI:NTL03PA00109; match to protein family HMM PF00510.
 
  
 0.601
MCA0116
Conserved hypothetical protein; Identified by similarity to GP:19914581; match to protein family HMM PF06803.
  
     0.581
MCA1729
Conserved domain protein; Identified by similarity to GP:19914581; match to protein family HMM PF06803.
  
     0.552
MCA0340
Putative membrane protein; Identified by similarity to GP:17133197.
  
     0.505
MCA1777
Conserved hypothetical protein; Identified by similarity to GP:7799507.
       0.490
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.