Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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lolAOuter membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (208 aa)    
Predicted Functional Partners:
MCA2624
Lipoprotein ABC transporter, permease protein LolE; Identified by similarity to SP:P75958; match to protein family HMM PF02687; match to protein family HMM TIGR02212.
 
 
 
 0.957
MCA1054
Putative outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
  
 
 
 0.919
MCA1782
ATPase, AAA family; Identified by similarity to GP:9948679; match to protein family HMM PF00004.
  
    0.845
MCA2172
ABC transporter, ATP-binding family protein; Identified by similarity to OMNI:NTL03PA02857; match to protein family HMM PF00005.
   
 
 0.822
lolD
Lipoprotein ABC transporter, ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
   
 
 0.822
bamA
Outer membrane protein, OMP85 family; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
   
 0.808
pal
OmpA family protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.797
mopB
Outer membrane protein MopB; Identified by similarity to GP:4104020; match to protein family HMM PF00691; match to protein family HMM PF02412.
 
 
 0.784
coaX
Putative transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family.
     
 0.779
MCA1779
Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA04279.
       0.773
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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