Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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[Homology]
Score
pmoBMethane monooxygenase, B subunit; Methane monooxygenase is responsible for the initial oxygenation of methane to methanol in methanotrophs. At least in vitro, specific quinols can replace NADH as reductants. (414 aa)    
Predicted Functional Partners:
pmoA
Methane monooxygenase, A subunit; Non-catalytic subunit of the methane monooxygenase that is responsible for the initial oxygenation of methane to methanol in methanotrophs. At least in vitro, specific quinols can replace NADH as reductants.
   
 0.999
pmoC3
Methane monooxygenase, C subunit; Identified by similarity to GP:14456716; match to protein family HMM PF04896.
   
 0.998
pmoC1
Methane monooxygenase, C subunit; Identified by similarity to GP:1894818; match to protein family HMM PF04896.
   
 0.998
pmoA2
Methane monooxygenase, A subunit; Identified by similarity to GP:1913912; match to protein family HMM PF02461.
   
 
 0.971
mmoX
Methane monooxygenase, A subunit, alpha chain; Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds; Belongs to the TmoA/XamoA family.
     
 0.960
mmoY
Methane monooxygenase, A subunit, beta chain; Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.
     
 0.960
mmoB
Methane monooxygenase, B subunit; The B protein acts as a regulator of electron flow through the soluble mmo complex, switching the enzyme from an oxidase to a hydroxylase in the presence of the substrate; Belongs to the TmoD/XamoD family.
     
 0.960
mmoZ
Methane monooxygenase, A subunit, gamma chain; Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.
     
 0.960
mmoD
Methane monooxygenase, D subunit.
     
 0.960
mmoC
Methane monooxygenase, C subunit; Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds. The component C is the iron-sulfur flavoprotein of sMMO.
     
 0.960
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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