Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MCA1872C4-dicarboxylate transporter; Identified by similarity to SP:P37312; match to protein family HMM PF00375; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (430 aa)    
Predicted Functional Partners:
sucB
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
    
 0.747
MCA1549
Putative succinate dehydrogenase, hydrophobic membrane anchor protein; Identified by similarity to SP:P10445; match to protein family HMM PF01127.
   
    0.723
MCA0840
Putative periplasmic amino acid-binding protein; Identified by similarity to SP:P30860.
     
 0.661
sucA
2-oxoglutarate dehydrogenase, E1 component; Identified by similarity to SP:P07015; match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239.
   
  
 0.646
MCA1264
ABC transporter, periplasmic substrate-binding protein; Identified by similarity to SP:P23843; match to protein family HMM PF00496.
      
 0.645
MCA1941
Putative sugar ABC transporter, sugar-binding protein; Identified by similarity to OMNI:NTL01LM1722; match to protein family HMM PF01547.
   
  
 0.621
MCA1268
ABC transporter, ATP-binding protein; Identified by similarity to OMNI:NTL03PA01808; match to protein family HMM PF00005; Belongs to the ABC transporter superfamily.
      
 0.618
MCA1924
ABC transporter, permease family protein; Identified by similarity to OMNI:TM0812; match to protein family HMM PF00528.
      
 0.618
MCA1521
Major facilitator family transporter; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690.
  
  
 0.604
MCA2107
Putative nonribosomal peptide synthetase; Identified by similarity to GP:9715733; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM TIGR01733; match to protein family HMM TIGR02353; Belongs to the ATP-dependent AMP-binding enzyme family.
 
   
 0.513
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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