Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA1891Conserved hypothetical protein; Identified by similarity to GP:6009450; match to protein family HMM PF02231. (877 aa)    
Predicted Functional Partners:
MCA1892
Conserved hypothetical protein; Identified by similarity to GP:19916049; match to protein family HMM PF04326.
 
     0.948
hsdM
Type I restriction-modification system, M subunit; Identified by similarity to GP:17984614; match to protein family HMM PF02384; match to protein family HMM PF02506; match to protein family HMM TIGR00497.
       0.776
MCA1889
Conserved hypothetical protein; Identified by similarity to GP:6723238.
       0.775
MCA1890
Type I restriction-modification system, S subunit; Identified by match to protein family HMM PF01420.
       0.773
MCA1893
Type I restriction-modification system, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification.
       0.773
MCA1894
Conserved hypothetical protein; Identified by similarity to GP:19919303; match to protein family HMM PF01863.
       0.773
MCA0474
ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00580; match to protein family HMM TIGR00614.
  
 
 0.757
MCA3010
Conserved hypothetical protein; Identified by similarity to GP:19916313; match to protein family HMM PF04326.
 
     0.618
scpA
Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.615
hepA
RNA polymerase-associated protein HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
  
 
 0.606
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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