Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
msrBPutative peptide methionine sulfoxide reductase; Identified by similarity to SP:P35593; match to protein family HMM PF01641; match to protein family HMM TIGR00357. (202 aa)    
Predicted Functional Partners:
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.992
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
       0.773
dsbD
Thiol:disulfide interchange protein, DsbD family; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
    
 
 0.767
MCA1956
ISMca1, transposase; Identified by match to protein family HMM PF01609.
       0.705
MCA1548
Putative succinate dehydrogenase, cytochrome b556 subunit; Identified by similarity to SP:P10446; match to protein family HMM PF01127.
   
    0.516
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
   
 
 0.489
bsaA
Glutathione peroxidase; Identified by similarity to SP:P52035; match to protein family HMM PF00255; Belongs to the glutathione peroxidase family.
  
  
 0.459
MCA1042
Thiol:disulfide interchange protein like protein.
   
 0.438
MCA1549
Putative succinate dehydrogenase, hydrophobic membrane anchor protein; Identified by similarity to SP:P10445; match to protein family HMM PF01127.
   
    0.437
dsbE-1
Thiol:disulfide interchange protein DsbE; Identified by similarity to SP:P33926; match to protein family HMM TIGR00385.
   
 0.433
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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