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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA1957Putative TonB-dependent receptor; Identified by similarity to OMNI:CC1750; match to protein family HMM PF00593; match to protein family HMM PF07715. (638 aa)    
Predicted Functional Partners:
MCA0439
TonB domain protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 
 0.601
MCA0441
TonB domain protein; Identified by match to protein family HMM PF03544; match to protein family HMM TIGR01352.
 
 
 
 0.596
MCA0668
TonB domain protein; Identified by match to protein family HMM PF03544; match to protein family HMM TIGR01352.
 
 
 
 0.583
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
   
 0.577
tolB
tolB protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 
 0.443
MCA2337
Putative TonB-dependent receptor; Identified by similarity to GP:17429800; match to protein family HMM TIGR01352.
   
 
 0.430
MCA1723
Outer membrane efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
  
   
 0.426
MCA0632
Biopolymer transport protein, ExbD/TolR family; Identified by match to protein family HMM PF02472.
 
   
 0.422
gltB
Glutamate synthase, large subunit; Identified by similarity to SP:P39812; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04897; match to protein family HMM PF04898.
      
 0.405
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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