Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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nagZbeta-N-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (334 aa)    
Predicted Functional Partners:
MCA2747
Cellulose-binding domain protein; Identified by match to protein family HMM PF00553.
     
 0.912
MCA2974
PKD domain protein.
     
  0.900
MCA2877
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01BH0675.
    0.896
MCA1985
Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156.
       0.821
MCA1986
Phosphorylase, family 2; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.
       0.821
pepA
Aminopeptidase A/I; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
    
 0.751
mpl
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.
  
   
 0.657
MCA0320
Putative ampG protein; Identified by similarity to SP:P36670; match to protein family HMM PF07690.
 
   
 0.642
ampD
N-acetyl-anhydromuramyl-L-alanine amidase; Identified by similarity to GP:14625828; match to protein family HMM PF01510.
 
   
 0.628
MCA0600
Conserved hypothetical protein; Identified by similarity to GP:4545243.
 
   
 0.538
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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