STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA2008Transglycosylase SLT domain protein; Identified by similarity to GP:17427990; match to protein family HMM PF01464. (214 aa)    
Predicted Functional Partners:
MCA2403
Putative membrane-bound lytic murein transglycosylase; Identified by similarity to SP:P23931; match to protein family HMM PF01464; match to protein family HMM PF01476.
  
  
 0.718
MCA1819
OmpA domain protein; Identified by match to protein family HMM PF00691.
 
    0.676
purT
Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.
       0.584
MCA1403
Membrane-bound lytic murein transglycosylase; Identified by similarity to SP:P23931; match to protein family HMM PF01464.
  
     0.572
MCA0831
Chemotaxis protein; Identified by similarity to SP:P18769; match to protein family HMM PF00072; match to protein family HMM PF01627; match to protein family HMM PF02518.
 
  
 0.476
MCA1674
Putative methyl-accepting chemotaxis protein; Identified by similarity to SP:P39216; match to protein family HMM PF00015; match to protein family HMM PF00672.
  
    0.471
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
      0.439
MCA0829
Methyltransferase, CheR family; Identified by match to protein family HMM PF00515; match to protein family HMM PF01739; match to protein family HMM PF07719.
 
     0.416
csrA
Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
 
    0.409
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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