STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA2045Transcriptional regulator, MarR family; Identified by match to protein family HMM PF01047. (190 aa)    
Predicted Functional Partners:
MCA0340
Putative membrane protein; Identified by similarity to GP:17133197.
  
     0.728
MCA0807
Copper resistance protein; Identified by match to protein family HMM PF05425.
  
     0.693
MCA2129
Identified by similarity to GP:4580028; match to protein family HMM PF07731; match to protein family HMM PF07732.
  
     0.690
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
       0.603
MCA1394
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.504
MCA2718
Conserved hypothetical protein; Identified by similarity to GP:1785478.
  
     0.487
MCA2048
Oxidoreductase, Gfo/Idh/MocA family; Identified by similarity to OMNI:CC1574; match to protein family HMM PF03446; match to protein family HMM PF07676.
     
 0.473
birA
birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
 0.465
MCA2410
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.456
MCA0564
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.446
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.