Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA2060Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA01838; match to protein family HMM PF06073. (161 aa)    
Predicted Functional Partners:
MCA2059
Nitrite/sulfite reductase protein; Identified by match to protein family HMM PF01077; match to protein family HMM PF03460.
 
  
 0.988
cysN
Putative nodQ bifunctional enzyme; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.627
MCA1512
TPR domain protein; Identified by similarity to SP:P21296; match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721.
  
     0.518
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
  
 0.505
cysH
Phosophoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite.
 
    0.501
MCA2058
Putative transporter.
       0.489
MCA1516
TPR domain protein, interruption-C; This gene is interrupted by an IS element; identified by similarity to GP:17430189; match to protein family HMM PF00515.
  
     0.462
MCA1511
TPR domain protein; Identified by match to protein family HMM PF00515.
  
     0.424
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.