| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCA2088 | MCA2884 | MCA2088 | MCA2884 | Conserved hypothetical protein; Identified by similarity to GP:17427822; match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | Cysteine desulfurase; Identified by similarity to SP:Q43884; match to protein family HMM PF00266. | 0.981 |
| MCA2088 | cysG | MCA2088 | MCA2089 | Conserved hypothetical protein; Identified by similarity to GP:17427822; match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.705 |
| MCA2088 | cysN | MCA2088 | MCA2628 | Conserved hypothetical protein; Identified by similarity to GP:17427822; match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | Putative nodQ bifunctional enzyme; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.526 |
| MCA2088 | dsrE | MCA2088 | MCA1331 | Conserved hypothetical protein; Identified by similarity to GP:17427822; match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | Intracellular sulfur oxidation protein DsrE; Identified by similarity to SP:O87896; match to protein family HMM PF02635. | 0.989 |
| MCA2088 | dsrF | MCA2088 | MCA1332 | Conserved hypothetical protein; Identified by similarity to GP:17427822; match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | Intracellular sulfur oxidation protein DsrF; Belongs to the DsrF/TusC family. | 0.576 |
| MCA2088 | iscS | MCA2088 | MCA0247 | Conserved hypothetical protein; Identified by similarity to GP:17427822; match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.981 |
| MCA2088 | moaC | MCA2088 | MCA2730 | Conserved hypothetical protein; Identified by similarity to GP:17427822; match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.517 |
| MCA2088 | moaD | MCA2088 | MCA3054 | Conserved hypothetical protein; Identified by similarity to GP:17427822; match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | Molybdopterin converting factor, subunit 1; Identified by similarity to SP:P30748; match to protein family HMM PF02597; match to protein family HMM TIGR01682; match to protein family HMM TIGR01687. | 0.520 |
| MCA2088 | nifS | MCA2088 | MCA0212 | Conserved hypothetical protein; Identified by similarity to GP:17427822; match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | Cysteine desulfurase; Identified by similarity to SP:Q43884; match to protein family HMM PF00266. | 0.981 |
| MCA2088 | trmU | MCA2088 | MCA1785 | Conserved hypothetical protein; Identified by similarity to GP:17427822; match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.517 |
| MCA2884 | MCA2088 | MCA2884 | MCA2088 | Cysteine desulfurase; Identified by similarity to SP:Q43884; match to protein family HMM PF00266. | Conserved hypothetical protein; Identified by similarity to GP:17427822; match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | 0.981 |
| MCA2884 | iscS | MCA2884 | MCA0247 | Cysteine desulfurase; Identified by similarity to SP:Q43884; match to protein family HMM PF00266. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.912 |
| MCA2884 | nifS | MCA2884 | MCA0212 | Cysteine desulfurase; Identified by similarity to SP:Q43884; match to protein family HMM PF00266. | Cysteine desulfurase; Identified by similarity to SP:Q43884; match to protein family HMM PF00266. | 0.912 |
| cysG | MCA2088 | MCA2089 | MCA2088 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Conserved hypothetical protein; Identified by similarity to GP:17427822; match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | 0.705 |
| cysG | cysN | MCA2089 | MCA2628 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Putative nodQ bifunctional enzyme; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.929 |
| cysN | MCA2088 | MCA2628 | MCA2088 | Putative nodQ bifunctional enzyme; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Conserved hypothetical protein; Identified by similarity to GP:17427822; match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | 0.526 |
| cysN | cysG | MCA2628 | MCA2089 | Putative nodQ bifunctional enzyme; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.929 |
| dsrE | MCA2088 | MCA1331 | MCA2088 | Intracellular sulfur oxidation protein DsrE; Identified by similarity to SP:O87896; match to protein family HMM PF02635. | Conserved hypothetical protein; Identified by similarity to GP:17427822; match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | 0.989 |
| dsrE | dsrF | MCA1331 | MCA1332 | Intracellular sulfur oxidation protein DsrE; Identified by similarity to SP:O87896; match to protein family HMM PF02635. | Intracellular sulfur oxidation protein DsrF; Belongs to the DsrF/TusC family. | 0.999 |
| dsrE | iscS | MCA1331 | MCA0247 | Intracellular sulfur oxidation protein DsrE; Identified by similarity to SP:O87896; match to protein family HMM PF02635. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.452 |
