node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCA2059 | cysC | MCA2059 | MCA2204 | Nitrite/sulfite reductase protein; Identified by match to protein family HMM PF01077; match to protein family HMM PF03460. | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.882 |
MCA2059 | cysD | MCA2059 | MCA2629 | Nitrite/sulfite reductase protein; Identified by match to protein family HMM PF01077; match to protein family HMM PF03460. | Sulfate adenylyltransferase, subunit 2; Identified by similarity to SP:O50273; match to protein family HMM PF01507; match to protein family HMM TIGR02039. | 0.887 |
MCA2059 | cysG | MCA2059 | MCA2089 | Nitrite/sulfite reductase protein; Identified by match to protein family HMM PF01077; match to protein family HMM PF03460. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.966 |
MCA2059 | cysH | MCA2059 | MCA2468 | Nitrite/sulfite reductase protein; Identified by match to protein family HMM PF01077; match to protein family HMM PF03460. | Phosophoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. | 0.998 |
MCA2059 | cysN | MCA2059 | MCA2628 | Nitrite/sulfite reductase protein; Identified by match to protein family HMM PF01077; match to protein family HMM PF03460. | Putative nodQ bifunctional enzyme; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.962 |
MCA2295 | MCA2299 | MCA2295 | MCA2299 | Precorrin-2 C20-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family. | CbiX protein; Identified by match to protein family HMM PF01903. | 0.992 |
MCA2295 | cysG | MCA2295 | MCA2089 | Precorrin-2 C20-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.958 |
MCA2295 | hemDX | MCA2295 | MCA3061 | Precorrin-2 C20-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III synthase/uroporphyrin-III C-methyltransferase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.912 |
MCA2299 | MCA2295 | MCA2299 | MCA2295 | CbiX protein; Identified by match to protein family HMM PF01903. | Precorrin-2 C20-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family. | 0.992 |
MCA2299 | cysG | MCA2299 | MCA2089 | CbiX protein; Identified by match to protein family HMM PF01903. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.996 |
MCA2299 | cysN | MCA2299 | MCA2628 | CbiX protein; Identified by match to protein family HMM PF01903. | Putative nodQ bifunctional enzyme; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.449 |
MCA2299 | hemDX | MCA2299 | MCA3061 | CbiX protein; Identified by match to protein family HMM PF01903. | uroporphyrinogen-III synthase/uroporphyrin-III C-methyltransferase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.415 |
cysC | MCA2059 | MCA2204 | MCA2059 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Nitrite/sulfite reductase protein; Identified by match to protein family HMM PF01077; match to protein family HMM PF03460. | 0.882 |
cysC | cysD | MCA2204 | MCA2629 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Sulfate adenylyltransferase, subunit 2; Identified by similarity to SP:O50273; match to protein family HMM PF01507; match to protein family HMM TIGR02039. | 0.998 |
cysC | cysG | MCA2204 | MCA2089 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.906 |
cysC | cysH | MCA2204 | MCA2468 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Phosophoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. | 0.999 |
cysC | cysN | MCA2204 | MCA2628 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Putative nodQ bifunctional enzyme; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.998 |
cysD | MCA2059 | MCA2629 | MCA2059 | Sulfate adenylyltransferase, subunit 2; Identified by similarity to SP:O50273; match to protein family HMM PF01507; match to protein family HMM TIGR02039. | Nitrite/sulfite reductase protein; Identified by match to protein family HMM PF01077; match to protein family HMM PF03460. | 0.887 |
cysD | cysC | MCA2629 | MCA2204 | Sulfate adenylyltransferase, subunit 2; Identified by similarity to SP:O50273; match to protein family HMM PF01507; match to protein family HMM TIGR02039. | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.998 |
cysD | cysG | MCA2629 | MCA2089 | Sulfate adenylyltransferase, subunit 2; Identified by similarity to SP:O50273; match to protein family HMM PF01507; match to protein family HMM TIGR02039. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.908 |