Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCA2124Putative colanic acid biosynthesis glycosyl transferase; Identified by similarity to SP:P71243; match to protein family HMM PF00534. (391 aa)    
Predicted Functional Partners:
MCA2125
Aminotransferase, DegT/DnrJ/EryC1/StrS family; Identified by match to protein family HMM PF01041; Belongs to the DegT/DnrJ/EryC1 family.
  
    0.707
djlA
DnaJ-like protein DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
  
   
 0.666
MCA0154
Glycosyl transferase, group 1 family protein; Identified by similarity to OMNI:VC0925; match to protein family HMM PF00534.
  
     0.663
MCA0474
ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00580; match to protein family HMM TIGR00614.
  
 
   0.651
MCA1153
Glycosyl transferase, group 1 family protein; Identified by match to protein family HMM PF00534.
  
     0.643
MCA1168
Putative colanic acid biosynthesis glycosyl transferase; Identified by similarity to SP:P32057; match to protein family HMM PF00534.
  
  
 0.642
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
  
 0.629
dnaK
dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 
 0.625
MCA0152
Glycosyl transferase, group 1 family protein; Identified by match to protein family HMM PF00534.
  
     0.589
MCA2126
Glycosyl transferase, group 1 family protein; Identified by match to protein family HMM PF00534.
 
    
0.538
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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