STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA2139Mg chelatase-related protein; Identified by match to protein family HMM PF01078; match to protein family HMM TIGR00368. (485 aa)    
Predicted Functional Partners:
MCA2841
Putative DNA processing protein DprA; Identified by similarity to SP:P43862; match to protein family HMM PF02481; match to protein family HMM TIGR00732.
 
 0.931
comF
Competence protein F; Identified by similarity to SP:P31773.
 
  
 0.875
rep
ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.
 
   
 0.845
MCA0184
Conserved hypothetical protein TIGR00252; Identified by similarity to GP:17430288; match to protein family HMM PF02021; match to protein family HMM TIGR00252; Belongs to the UPF0102 family.
 
  
 0.734
def-2
Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
      0.703
MCA2138
Conserved hypothetical protein; Identified by similarity to SP:Q46868; match to protein family HMM PF04380.
       0.659
MCA2627
DNA internalization-related competence protein ComEC/Rec2; Identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361.
 
  
 0.652
MCA0767
Putative competence protein ComE; Identified by similarity to GP:10505056; match to protein family HMM TIGR00426.
  
  
 0.544
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
  
   
 0.453
MCA2141
Hypothetical protein; Identified by Glimmer2; putative.
       0.442
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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