MCA2158 protein (Methylococcus capsulatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MCA2158

Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF06445. (294 aa)

Predicted Functional Partners:

MCA3027

0.554

MCA0825

0.526

MCA1744

0.473

MCA2962

0.459

MCA2808

0.451

rpoA

0.446

MCA2512

0.439

polI

0.428

MCA1204

0.404

Your Current Organism:

Methylococcus capsulatus

NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCA0825	MCA2158	MCA0825	MCA2158	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165.	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF06445.	0.526
MCA0825	MCA2808	MCA0825	MCA2808	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165.	Conserved hypothetical protein; Identified by similarity to GP:17427115; match to protein family HMM PF00903.	0.659
MCA0825	MCA2962	MCA0825	MCA2962	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165.	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165.	0.445
MCA0825	MCA3027	MCA0825	MCA3027	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165.	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM TIGR01199.	0.504
MCA1204	MCA2158	MCA1204	MCA2158	Sensory box histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00785; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM TIGR00229.	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF06445.	0.404
MCA1204	polI	MCA1204	MCA2573	Sensory box histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00785; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM TIGR00229.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.560
MCA1744	MCA2158	MCA1744	MCA2158	Acetyltransferase, GNAT family; Identified by similarity to GP:1652538; match to protein family HMM PF00583.	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF06445.	0.473
MCA2158	MCA0825	MCA2158	MCA0825	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF06445.	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165.	0.526
MCA2158	MCA1204	MCA2158	MCA1204	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF06445.	Sensory box histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00785; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM TIGR00229.	0.404
MCA2158	MCA1744	MCA2158	MCA1744	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF06445.	Acetyltransferase, GNAT family; Identified by similarity to GP:1652538; match to protein family HMM PF00583.	0.473
MCA2158	MCA2512	MCA2158	MCA2512	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF06445.	Acid phosphatase; Identified by similarity to GP:7650481; match to protein family HMM PF04185.	0.439
MCA2158	MCA2808	MCA2158	MCA2808	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF06445.	Conserved hypothetical protein; Identified by similarity to GP:17427115; match to protein family HMM PF00903.	0.451
MCA2158	MCA2962	MCA2158	MCA2962	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF06445.	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165.	0.459
MCA2158	MCA3027	MCA2158	MCA3027	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF06445.	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM TIGR01199.	0.554
MCA2158	polI	MCA2158	MCA2573	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF06445.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.428
MCA2158	rpoA	MCA2158	MCA2347	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF06445.	DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.446
MCA2512	MCA2158	MCA2512	MCA2158	Acid phosphatase; Identified by similarity to GP:7650481; match to protein family HMM PF04185.	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF06445.	0.439
MCA2808	MCA0825	MCA2808	MCA0825	Conserved hypothetical protein; Identified by similarity to GP:17427115; match to protein family HMM PF00903.	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165.	0.659
MCA2808	MCA2158	MCA2808	MCA2158	Conserved hypothetical protein; Identified by similarity to GP:17427115; match to protein family HMM PF00903.	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF06445.	0.451
MCA2962	MCA0825	MCA2962	MCA0825	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165.	Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165.	0.445

page 1 of 2

Server load: low (40%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Textmining

Coexpression

Databases

Fusion

© STRING Consortium 2025

Credits

Access

Info

About