STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA2166Conserved hypothetical protein; Identified by similarity to GP:9946550. (207 aa)    
Predicted Functional Partners:
MCA2165
Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA00671.
  
 0.998
dnaE2
Putative DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
  
 0.981
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
 
   
 0.936
MCA0860
Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA05280; match to protein family HMM PF04340.
  
     0.530
MCA0130
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.467
MCA1469
Putative sigma-E factor regulatory protein; Identified by similarity to SP:P46186.
  
     0.446
MCA1289
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.427
MCA0323
Conserved domain protein; Identified by similarity to GP:17429805.
  
     0.423
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.