Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA2202Aspartate aminotransferase; Identified by similarity to SP:P23034; match to protein family HMM PF00155. (393 aa)    
Predicted Functional Partners:
pheA
Chorismate mutase/prephenate dehydratase; Identified by similarity to SP:P27603; match to protein family HMM PF00800; match to protein family HMM PF01817; match to protein family HMM PF01842; match to protein family HMM TIGR01807.
 
 
 0.992
argG
Argininosuccinate synthase; Identified by similarity to SP:O34347; match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
   
 0.925
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.920
hisC-2
Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
0.912
gltD
Glutamate synthase, NADH/NADPH small subunit; Identified by similarity to GP:17429987; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01317.
   
 
 0.912
argA
N-acetylglutamate synthase; Identified by similarity to SP:P08205; match to protein family HMM PF00583; match to protein family HMM PF00696; match to protein family HMM TIGR01890; Belongs to the acetyltransferase family. ArgA subfamily.
  
 
 0.912
MCA1021
Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.
  
  
0.911
MCA1684
Conserved domain protein; Identified by similarity to GP:11830835; match to protein family HMM PF05088.
     
 0.907
tyrA
Prephenate dehydrogenase; Identified by match to protein family HMM PF02153.
    
 0.906
gluD
Glutamate dehydrogenase, NAD-specific; Identified by similarity to SP:P80053; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.905
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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