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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA2211Identified by match to protein family HMM PF00899; match to protein family HMM PF05237. (248 aa)    
Predicted Functional Partners:
thiS
Thiamine biosynthesis protein ThiS; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 0.997
moaD
Molybdopterin converting factor, subunit 1; Identified by similarity to SP:P30748; match to protein family HMM PF02597; match to protein family HMM TIGR01682; match to protein family HMM TIGR01687.
  
 0.986
nifS
Cysteine desulfurase; Identified by similarity to SP:Q43884; match to protein family HMM PF00266.
   
 0.972
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
   
 0.972
MCA2884
Cysteine desulfurase; Identified by similarity to SP:Q43884; match to protein family HMM PF00266.
   
 0.972
moaE
Molybdopterin converting factor, subunit 2; Identified by similarity to SP:P30749; match to protein family HMM PF02391.
 
 0.939
MCA1742
Rhodanese-like domain protein; Identified by match to protein family HMM PF00581.
    
 0.903
thiC
Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
 0.886
MCA1816
Rhodanese-like domain; Identified by match to protein family HMM PF00581.
    
 0.822
MCA0629
Putative phosphomethylpyrimidine kinase; Identified by similarity to SP:P55882.
 
  
 0.804
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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