Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCA2276Phage SPO1 DNA polymerase-related protein; Identified by match to protein family HMM PF03167; match to protein family HMM TIGR00758. (243 aa)    
Predicted Functional Partners:
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
       0.781
rimI
Ribosomal-protein-alanine acetyltransferase; Identified by similarity to SP:P09453; match to protein family HMM PF00583; match to protein family HMM TIGR01575.
  
    0.747
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
      0.714
def-2
Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
      0.659
oadA
Oxaloacetate decarboxylase, alpha subunit; Identified by match to protein family HMM PF00364; match to protein family HMM PF00682; match to protein family HMM PF02436; match to protein family HMM TIGR01108.
  
    0.524
pssA
CDP-diacylglycerol--serine O-phosphatidyltransferase; Identified by similarity to SP:Q48269; match to protein family HMM PF01066; match to protein family HMM TIGR00473; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.461
MCA2210
Conserved hypothetical protein; Identified by similarity to GP:15980083; match to protein family HMM PF00814.
  
    0.407
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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