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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBCobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (429 aa)    
Predicted Functional Partners:
cobH
precorrin-8X methylmutase; Identified by similarity to SP:P21638; match to protein family HMM PF02570.
 
 0.997
cobA
cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
 
 0.990
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.985
MCA2289
Nitroreductase family protein; Identified by similarity to GP:17431084; match to protein family HMM PF00881; match to protein family HMM TIGR02476.
  
 0.983
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
  
 0.979
MCA2293
precorrin-3B C17-methyltransferase/conserved domain protein; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01466.
 
  
 0.961
MCA2295
Precorrin-2 C20-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family.
  
 0.921
MCA1814
Putative ATP:cob(I)alamin adenosyltransferase; Identified by similarity to GP:17429685; match to protein family HMM PF01923; match to protein family HMM TIGR00636; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.916
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
 0.913
cobU
Bifunctional cobalamin biosynthesis protein CobU; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
 
  
 0.895
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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