Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA2465Putative membrane protein; Identified by similarity to OMNI:NTL03ST2793; match to protein family HMM PF07690. (403 aa)    
Predicted Functional Partners:
MCA2466
Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA05495.
       0.668
MCA1569
Putative long-chain fatty-acid-CoA ligase; Identified by similarity to SP:P94547; match to protein family HMM PF00501.
    
 0.641
MCA0864
Conserved hypothetical protein; Identified by similarity to OMNI:VC2536; match to protein family HMM PF04751; Belongs to the UPF0307 family.
  
     0.522
gltB
Glutamate synthase, large subunit; Identified by similarity to SP:P39812; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04897; match to protein family HMM PF04898.
      
 0.469
gshA
Glutamate--cysteine ligase; Identified by similarity to SP:P06980; match to protein family HMM PF04262; match to protein family HMM TIGR01434; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
       0.455
MCA2571
Radical SAM domain protein; Identified by similarity to GP:17130075; match to protein family HMM PF04055.
  
     0.410
cysH
Phosophoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite.
       0.407
parC
DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
  
 0.405
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: low (14%) [HD]