Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ugdUDP-glucose 6-dehydrogenase; Identified by similarity to SP:O54068; match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721. (442 aa)    
Predicted Functional Partners:
MCA1165
Identified by match to protein family HMM PF01370; match to protein family HMM PF07993.
 
 0.991
rfbA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.979
galU
UTP-glucose-1-phosphate uridylyltransferase; Identified by similarity to OMNI:NMB0638; match to protein family HMM PF00483; match to protein family HMM TIGR01099.
 
 0.977
MCA2449
Capsular polysaccharide biosynthesis protein I; Identified by similarity to SP:P39858; match to protein family HMM PF01370; match to protein family HMM PF07993.
 0.945
galE-2
UDP-glucose 4-epimerase; Identified by similarity to SP:Q59083; match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM TIGR01179; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
 
 0.941
MCA2033
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.935
rfbC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
  
 0.900
rfbB
dTDP-glucose 4,6-dehydratase; Identified by similarity to SP:P55295; match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM TIGR01181; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.890
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.
    
 0.861
MCA1772
Polysaccharide biosynthesis protein; Identified by similarity to GP:19918600; match to protein family HMM PF01943.
  
  
 0.780
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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