| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCA0431 | MCA2059 | MCA0431 | MCA2059 | Flavodoxin domain protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | Nitrite/sulfite reductase protein; Identified by match to protein family HMM PF01077; match to protein family HMM PF03460. | 0.997 |
| MCA0431 | cysK | MCA0431 | MCA1022 | Flavodoxin domain protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.942 |
| MCA0431 | metH | MCA0431 | MCA1545 | Flavodoxin domain protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.799 |
| MCA0431 | metZ | MCA0431 | MCA2488 | Flavodoxin domain protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.919 |
| MCA0431 | sqr | MCA0431 | MCA2155 | Flavodoxin domain protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | Sulfide-quinone reductase; Identified by similarity to GP:2385380; match to protein family HMM PF07992. | 0.901 |
| MCA1021 | ahcY | MCA1021 | MCA0138 | Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.900 |
| MCA1021 | cysK | MCA1021 | MCA1022 | Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155. | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.954 |
| MCA1021 | hom | MCA1021 | MCA0597 | Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155. | Homoserine dehydrogenase; Identified by similarity to SP:P29365; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. | 0.800 |
| MCA1021 | metE | MCA1021 | MCA2260 | Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.905 |
| MCA1021 | metH | MCA1021 | MCA1545 | Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.934 |
| MCA1021 | metZ | MCA1021 | MCA2488 | Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.957 |
| MCA2059 | MCA0431 | MCA2059 | MCA0431 | Nitrite/sulfite reductase protein; Identified by match to protein family HMM PF01077; match to protein family HMM PF03460. | Flavodoxin domain protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | 0.997 |
| MCA2059 | cysK | MCA2059 | MCA1022 | Nitrite/sulfite reductase protein; Identified by match to protein family HMM PF01077; match to protein family HMM PF03460. | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.954 |
| MCA2059 | metH | MCA2059 | MCA1545 | Nitrite/sulfite reductase protein; Identified by match to protein family HMM PF01077; match to protein family HMM PF03460. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.462 |
| MCA2059 | metZ | MCA2059 | MCA2488 | Nitrite/sulfite reductase protein; Identified by match to protein family HMM PF01077; match to protein family HMM PF03460. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.941 |
| MCA2059 | sqr | MCA2059 | MCA2155 | Nitrite/sulfite reductase protein; Identified by match to protein family HMM PF01077; match to protein family HMM PF03460. | Sulfide-quinone reductase; Identified by similarity to GP:2385380; match to protein family HMM PF07992. | 0.901 |
| ahcY | MCA1021 | MCA0138 | MCA1021 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155. | 0.900 |
| ahcY | cysK | MCA0138 | MCA1022 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.839 |
| ahcY | hom | MCA0138 | MCA0597 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Homoserine dehydrogenase; Identified by similarity to SP:P29365; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. | 0.815 |
| ahcY | metE | MCA0138 | MCA2260 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.978 |
