Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
arsCArsenate reductase; Identified by similarity to SP:P37311; match to protein family HMM PF03960; match to protein family HMM TIGR00014. (116 aa)    
Predicted Functional Partners:
MCA1387
Putative arsenate reductase; Identified by similarity to SP:P45947; match to protein family HMM PF01451; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
 
  
 0.919
MCA1346
Sodium/bile acid symporter family protein; Identified by match to protein family HMM PF01758.
    
 0.811
MCA1388
Transcriptional regulator, ArsR family; Identified by match to protein family HMM PF01022.
    
 0.798
wrbA
Trp repressor-binding protein; Identified by similarity to SP:P30849; match to protein family HMM PF00258; Belongs to the WrbA family.
  
    0.792
MCA2265
Conserved hypothetical protein; Identified by similarity to SP:P45945; match to protein family HMM PF00903.
     0.763
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
      0.725
MCA1330
Conserved hypothetical protein; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
 
  
 0.721
merA
Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
      
 0.708
MCA2264
Heavy metal efflux pump, CzcA family; Identified by match to protein family HMM PF00873; match to protein family HMM TIGR00914; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
   
 0.662
ispF
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
  
  
 0.660
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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