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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA2522DnaA domain protein; Identified by similarity to OMNI:NTL03PA00948; Belongs to the DnaA family. HdA subfamily. (232 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.966
panE
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
       0.810
MCA2524
Conserved domain protein; Identified by similarity to OMNI:NTL01SS02345.
       0.773
wrbA
Trp repressor-binding protein; Identified by similarity to SP:P30849; match to protein family HMM PF00258; Belongs to the WrbA family.
       0.739
arsC
Arsenate reductase; Identified by similarity to SP:P37311; match to protein family HMM PF03960; match to protein family HMM TIGR00014.
       0.677
rpmE
Ribosomal protein L31; Binds the 23S rRNA.
   
    0.664
MCA3004
Pyridine nucleotide-disulphide oxidoreductase family protein; Identified by match to protein family HMM PF00070; match to protein family HMM PF00581; match to protein family HMM PF02852; match to protein family HMM PF07992.
   
    0.648
MCA2087
HAD-superfamily subfamily IB hydrolase, TIGR01490; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490.
      0.621
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.
 
  
 0.602
truD
Conserved hypothetical protein TIGR00094; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
 
     0.597
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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