Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA2533Carboxyl-terminal protease; Identified by similarity to OMNI:NTL03PA05135; match to protein family HMM PF00595; match to protein family HMM PF03572; match to protein family HMM TIGR00225; Belongs to the peptidase S41A family. (441 aa)    
Predicted Functional Partners:
MCA2534
Peptidase, family M23/M37 domain protein; Identified by match to protein family HMM PF01551.
  
  
 0.832
MCA2789
Identified by match to protein family HMM PF00877.
    
 
 0.799
MCA0829
Methyltransferase, CheR family; Identified by match to protein family HMM PF00515; match to protein family HMM PF01739; match to protein family HMM PF07719.
   
   0.717
MCA0769
Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by similarity to SP:P52647; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM PF02775; match to protein family HMM TIGR02176.
    
 
 0.651
rppH
MutT/nudix family protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
    
 0.651
MCA1053
TPR domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721.
  
 
   0.587
oadA
Oxaloacetate decarboxylase, alpha subunit; Identified by match to protein family HMM PF00364; match to protein family HMM PF00682; match to protein family HMM PF02436; match to protein family HMM TIGR01108.
  
    0.527
MCA2532
Heat shock protein, Hsp20 family; Identified by similarity to SP:Q06823; match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family.
       0.527
MCA0574
Putative membrane-associated zinc metalloprotease; Identified by match to protein family HMM PF00595; match to protein family HMM PF02163; match to protein family HMM TIGR00054.
 
  
 0.513
MCA2535
Transcriptional regulator, ArsR family; Identified by match to protein family HMM PF01022.
     
 0.464
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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