Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MCA2576Formate dehydrogenase, alpha subunit; Identified by similarity to SP:P07658; match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01591. (925 aa)    
Predicted Functional Partners:
MCA2577
Putative dehydrogenase subunit; Identified by similarity to GP:4007678; match to protein family HMM PF01257; match to protein family HMM PF01512.
 0.998
MCA1393
Formate dehydrogenase, gamma subunit; Identified by similarity to GP:3724143; match to protein family HMM PF01257.
 
 0.984
MCA1208
Putative formate dehydrogenase, gamma subunit; Identified by similarity to SP:P32174; match to protein family HMM TIGR01583.
  
 
 0.981
MCA1389
Formate dehydrogenase, delta subunit; Identified by similarity to GP:3724147.
  
 0.978
MCA1392
Formate dehydrogenase, beta subunit; Identified by similarity to GP:3724144; match to protein family HMM PF01512.
 
 0.962
MCA1209
Formate dehydrogenase, iron-sulfur subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
 
 
 0.956
MCA0431
Flavodoxin domain protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
 
 
 0.931
MCA1391
Formate dehydrogenase, alpha subunit; Identified by similarity to GP:17743211; match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01591.
  
  
0.917
MCA1138
Hydrogenase subunit; Identified by similarity to SP:P77329; match to protein family HMM PF00329; match to protein family HMM PF00346.
  
 
 0.909
MCA1210
Formate dehydrogenase, alpha subunit; Identified by similarity to SP:P32176; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR01553.
  
  
 
0.904
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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