Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lolDLipoprotein ABC transporter, ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (224 aa)    
Predicted Functional Partners:
MCA2624
Lipoprotein ABC transporter, permease protein LolE; Identified by similarity to SP:P75958; match to protein family HMM PF02687; match to protein family HMM TIGR02212.
 0.995
pstB
Phosphate ABC transporter, ATP-binding protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
  
0.912
msbA
Lipid A export ATP-binding/permease protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
   
0.881
MCA1214
ABC transporter, ATP-binding/permease protein; Identified by similarity to OMNI:NMB0264; match to protein family HMM PF00005; match to protein family HMM PF00664.
   
0.873
MCA0589
Putative nitrate transporter; Identified by similarity to SP:P38043.
 
    
 0.848
lolA
Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
   
 
 0.822
MCA1280
ABC transporter, ATP-binding protein; Identified by similarity to OMNI:NTL01SMB00184; match to protein family HMM PF00005.
 
    
0.801
fur
Ferric uptake regulation protein; Identified by similarity to SP:P06975; match to protein family HMM PF01475; Belongs to the Fur family.
       0.762
MCA1808
Putative ABC-transporter permease protein; Gene luster supports this as an ABC transporter; identified by match to protein family HMM PF02687.
  
 
 0.737
MCA1054
Putative outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
    
 
 0.671
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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