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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbbLRibulose bisphosphate carboxylase, large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. (473 aa)    
Predicted Functional Partners:
cbbS
Ribulose bisphosphate carboxylase, small subunit; Identified by similarity to GP:17646562; match to protein family HMM PF00101.
 
 0.999
cbbP
Phosphoribulokinase; Identified by similarity to SP:P23015; match to protein family HMM PF00485.
 
 
 0.934
cbbZ
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
    
 0.922
MCA1408
Conserved hypothetical protein; Identified by similarity to OMNI:CC2910.
     
  0.900
cbbQ
cbbQ protein; Identified by similarity to GP:4105515; match to protein family HMM PF07728.
 
   
 0.880
cbbO
cbbO protein; Identified by similarity to GP:4433775; match to protein family HMM PF00092.
 
   
 0.876
mtnD
Dioxygenase, ARD/ARD' family; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
  
  
 0.844
MCA2107
Putative nonribosomal peptide synthetase; Identified by similarity to GP:9715733; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM TIGR01733; match to protein family HMM TIGR02353; Belongs to the ATP-dependent AMP-binding enzyme family.
    
 
 0.797
MCA2797
Carbonic anhydrase, family 3; Identified by similarity to SP:P45770.
    
 
 0.710
MCA3039
Rubisco operon transcriptional regulator; Identified by similarity to SP:P25544; match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
   
 0.637
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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