Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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MCA2772Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (97 aa)    
Predicted Functional Partners:
pepP
Xaa-pro aminopeptidase; Identified by similarity to SP:P15034; match to protein family HMM PF00557; match to protein family HMM PF05195; Belongs to the peptidase M24B family.
 
   
 0.818
MCA3090
Conserved domain protein; Identified by similarity to OMNI:NTL03PA05053; match to protein family HMM PF05036.
  
   
 0.772
ihfA
Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
   
    0.769
ftsL
Putative cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
   
 0.767
MCA2439
Putative cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.
 
   
 0.740
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.709
MCA2771
Conserved hypothetical protein; Identified by similarity to SP:Q9HTW5; match to protein family HMM TIGR02292; Belongs to the UPF0149 family.
  
  
 0.706
MCA1054
Putative outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
  
     0.690
MCA2337
Putative TonB-dependent receptor; Identified by similarity to GP:17429800; match to protein family HMM TIGR01352.
 
    0.678
ubiH
2-octaprenyl-6-methoxyphenol hydroxylase; Identified by similarity to SP:P25534; match to protein family HMM PF01360; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988.
     
 0.672
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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