Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCA2776Pyridine nucleotide-disulphide oxidoreductase family protein; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992. (380 aa)    
Predicted Functional Partners:
MCA0987
Rieske 2Fe-2S family protein; Identified by similarity to GP:17942398; match to protein family HMM PF00355.
 
 
 0.955
MCA0253
Ferredoxin, 2Fe-2S; Identified by similarity to SP:P25528; match to protein family HMM PF00111; match to protein family HMM TIGR02007.
  
 
 0.907
MCA0216
Putative ferredoxin, 2Fe-2S; Identified by similarity to SP:P25528; match to protein family HMM PF00111.
     
  0.900
MCA1254
Rubredoxin; Identified by similarity to SP:P09947; match to protein family HMM PF00301.
  
 
 0.860
MCA1209
Formate dehydrogenase, iron-sulfur subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
   
 
 0.719
nasA
Nitrate reductase; Identified by similarity to SP:Q06457; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04324; match to protein family HMM PF04879; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
  
 0.703
gltB
Glutamate synthase, large subunit; Identified by similarity to SP:P39812; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04897; match to protein family HMM PF04898.
  
  
 0.648
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
  
  
 0.567
nirD
Nitrite reductase [NAD(P)H], small subunit; Identified by similarity to SP:P42436; match to protein family HMM PF00355; match to protein family HMM TIGR02378.
  
  
 0.540
cyp51
Cytochrome P450 51; Identified by similarity to SP:P77901; match to protein family HMM PF00067.
 
  
 0.524
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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