Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA2806Pyridoxal-dependent decarboxylase domain protein; Identified by similarity to OMNI:NTL01BH0567; match to protein family HMM PF00282. (560 aa)    
Predicted Functional Partners:
MCA0769
Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by similarity to SP:P52647; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM PF02775; match to protein family HMM TIGR02176.
     
 0.559
MCA2703
Serine protease, trypsin family; Identified by match to protein family HMM PF00089.
  
 
 0.554
MCA2807
Putative methyltransferase.
       0.538
hisB
Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475.
       0.533
MCA2808
Conserved hypothetical protein; Identified by similarity to GP:17427115; match to protein family HMM PF00903.
 
    0.459
hisH
Amidotransferase HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
       0.445
MCA1238
Polyketide synthase; Identified by similarity to GP:24575128; match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01590; match to protein family HMM PF02801.
 
   
 0.431
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by match to protein family HMM PF00977; match to protein family HMM TIGR00007.
     
 0.426
hisE
phosphoribosyl-ATP pyrophosphatase; Identified by similarity to SP:O30723; match to protein family HMM PF01503.
     
 0.419
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
     
 0.419
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.