Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCA28134Fe-4S binding domain protein; Identified by match to protein family HMM PF00037. (450 aa)    
Predicted Functional Partners:
MCA2812
Transcriptional regulator, MarR family; Identified by match to protein family HMM PF01047.
 
     0.743
nnrD
YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family.
     
 0.569
MCA2814
Efflux transporter, RND family, MFP subunit; Identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.484
MCA2815
Identified by match to protein family HMM PF00873; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.484
MCA0453
Identified by match to protein family HMM PF01656.
  
     0.448
budA
Alpha-acetolactate decarboxylase; Converts acetolactate into acetoin.
  
     0.445
MCA0316
Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440.
  
     0.433
MCA0685
Conserved domain protein; Identified by similarity to GP:3462874; match to protein family HMM PF03734.
  
     0.428
MCA2811
Hypothetical protein; Identified by Glimmer2; putative.
       0.426
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.414
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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