typA protein (Methylococcus capsulatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

typA

GTP-binding protein TypA; Identified by similarity to GP:9857266; match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394. (606 aa)

Predicted Functional Partners:

guaA

0.720

gltB

0.600

rpsI

0.556

polI

0.548

MCA2850

0.530

rplA

0.529

MCA2847

0.506

sun

0.505

MCA2851

0.488

rpmI

0.487

Your Current Organism:

Methylococcus capsulatus

NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCA2847	MCA2850	MCA2847	MCA2850	Putative nitrogen regulation protein NtrY; Identified by similarity to SP:Q04850; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00785; match to protein family HMM PF02518; match to protein family HMM TIGR00229.	Conserved hypothetical protein; Identified by similarity to GP:17428157.	0.829
MCA2847	MCA2851	MCA2847	MCA2851	Putative nitrogen regulation protein NtrY; Identified by similarity to SP:Q04850; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00785; match to protein family HMM PF02518; match to protein family HMM TIGR00229.	Rhodanese domain protein; Identified by similarity to GP:17427305; match to protein family HMM PF00581.	0.773
MCA2847	sun	MCA2847	MCA2845	Putative nitrogen regulation protein NtrY; Identified by similarity to SP:Q04850; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00785; match to protein family HMM PF02518; match to protein family HMM TIGR00229.	Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	0.821
MCA2847	typA	MCA2847	MCA2852	Putative nitrogen regulation protein NtrY; Identified by similarity to SP:Q04850; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00785; match to protein family HMM PF02518; match to protein family HMM TIGR00229.	GTP-binding protein TypA; Identified by similarity to GP:9857266; match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394.	0.506
MCA2850	MCA2847	MCA2850	MCA2847	Conserved hypothetical protein; Identified by similarity to GP:17428157.	Putative nitrogen regulation protein NtrY; Identified by similarity to SP:Q04850; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00785; match to protein family HMM PF02518; match to protein family HMM TIGR00229.	0.829
MCA2850	MCA2851	MCA2850	MCA2851	Conserved hypothetical protein; Identified by similarity to GP:17428157.	Rhodanese domain protein; Identified by similarity to GP:17427305; match to protein family HMM PF00581.	0.811
MCA2850	sun	MCA2850	MCA2845	Conserved hypothetical protein; Identified by similarity to GP:17428157.	Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	0.805
MCA2850	typA	MCA2850	MCA2852	Conserved hypothetical protein; Identified by similarity to GP:17428157.	GTP-binding protein TypA; Identified by similarity to GP:9857266; match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394.	0.530
MCA2851	MCA2847	MCA2851	MCA2847	Rhodanese domain protein; Identified by similarity to GP:17427305; match to protein family HMM PF00581.	Putative nitrogen regulation protein NtrY; Identified by similarity to SP:Q04850; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00785; match to protein family HMM PF02518; match to protein family HMM TIGR00229.	0.773
MCA2851	MCA2850	MCA2851	MCA2850	Rhodanese domain protein; Identified by similarity to GP:17427305; match to protein family HMM PF00581.	Conserved hypothetical protein; Identified by similarity to GP:17428157.	0.811
MCA2851	sun	MCA2851	MCA2845	Rhodanese domain protein; Identified by similarity to GP:17427305; match to protein family HMM PF00581.	Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	0.773
MCA2851	typA	MCA2851	MCA2852	Rhodanese domain protein; Identified by similarity to GP:17427305; match to protein family HMM PF00581.	GTP-binding protein TypA; Identified by similarity to GP:9857266; match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394.	0.488
gltB	guaA	MCA2039	MCA0290	Glutamate synthase, large subunit; Identified by similarity to SP:P39812; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04897; match to protein family HMM PF04898.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.686
gltB	polI	MCA2039	MCA2573	Glutamate synthase, large subunit; Identified by similarity to SP:P39812; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04897; match to protein family HMM PF04898.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.501
gltB	typA	MCA2039	MCA2852	Glutamate synthase, large subunit; Identified by similarity to SP:P39812; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04897; match to protein family HMM PF04898.	GTP-binding protein TypA; Identified by similarity to GP:9857266; match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394.	0.600
guaA	gltB	MCA0290	MCA2039	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Glutamate synthase, large subunit; Identified by similarity to SP:P39812; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04897; match to protein family HMM PF04898.	0.686
guaA	polI	MCA0290	MCA2573	GMP synthase; Catalyzes the synthesis of GMP from XMP.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.720
guaA	rplA	MCA0290	MCA1063	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.913
guaA	rpmI	MCA0290	MCA0695	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Ribosomal protein L35; Identified by similarity to SP:P07085; match to protein family HMM PF01632; match to protein family HMM TIGR00001; Belongs to the bacterial ribosomal protein bL35 family.	0.433
guaA	rpsI	MCA0290	MCA0905	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Ribosomal protein S9; Identified by similarity to SP:P02363; match to protein family HMM PF00380; Belongs to the universal ribosomal protein uS9 family.	0.639

page 1 of 3

Server load: low (16%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About