Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCA2888Putative type IV pilus biogenesis protein PilF; Identified by similarity to GP:1162960; match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM TIGR02521. (255 aa)    
Predicted Functional Partners:
rlmN
Conserved hypothetical protein TIGR00048; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
  
    0.825
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
       0.821
pilO
Type 4 fimbrial biogenesis protein PilO; Identified by similarity to OMNI:NTL03PA05043; match to protein family HMM PF04350.
  
   
 0.760
pilP
Type 4 fimbrial biogenesis protein PilP; Identified by similarity to OMNI:NTL03PA05042; match to protein family HMM PF04351.
  
   
 0.752
pilN
Type 4 fimbrial biogenesis protein PilN; Identified by similarity to OMNI:NTL03PA05044; match to protein family HMM PF05137.
  
   
 0.747
hisS
histidyl-tRNA synthetase; Identified by similarity to SP:P04804; match to protein family HMM PF00587; match to protein family HMM PF03129; match to protein family HMM TIGR00442.
  
    0.733
pilM
Type 4 fimbrial biogenesis protein PilM; Identified by similarity to OMNI:NTL03PA05045; match to protein family HMM TIGR01175.
  
   
 0.709
pilQ
Fimbrial assembly protein PilQ; Identified by similarity to SP:P34750; match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM PF07660; match to protein family HMM TIGR02515.
  
   
 0.708
MCA2890
Conserved hypothetical protein; Identified by similarity to GP:9949974; match to protein family HMM PF07721.
       0.708
bamB
Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
       0.708
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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