node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCA1985 | apt | MCA1985 | MCA0816 | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.939 |
MCA1985 | gmk | MCA1985 | MCA2975 | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.930 |
MCA1985 | guaA | MCA1985 | MCA0290 | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.954 |
MCA1985 | surE | MCA1985 | MCA2418 | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
MCA2543 | gmk | MCA2543 | MCA2975 | Ribonucleoside reductase precursor; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.909 |
MCA2543 | guaA | MCA2543 | MCA0290 | Ribonucleoside reductase precursor; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.560 |
MCA2543 | ndk | MCA2543 | MCA2886 | Ribonucleoside reductase precursor; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.911 |
MCA2543 | nrdA | MCA2543 | MCA1634 | Ribonucleoside reductase precursor; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.951 |
MCA2543 | nrdB | MCA2543 | MCA1637 | Ribonucleoside reductase precursor; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.997 |
MCA2543 | pyk | MCA2543 | MCA2597 | Ribonucleoside reductase precursor; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Pyruvate kinase; Identified by similarity to SP:P21599; match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.903 |
MCA2543 | spoT | MCA2543 | MCA2023 | Ribonucleoside reductase precursor; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
apt | MCA1985 | MCA0816 | MCA1985 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | 0.939 |
apt | gmk | MCA0816 | MCA2975 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.963 |
apt | guaA | MCA0816 | MCA0290 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.991 |
apt | surE | MCA0816 | MCA2418 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.916 |
gmk | MCA1985 | MCA2975 | MCA1985 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | 0.930 |
gmk | MCA2543 | MCA2975 | MCA2543 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside reductase precursor; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.909 |
gmk | apt | MCA2975 | MCA0816 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.963 |
gmk | guaA | MCA2975 | MCA0290 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.965 |
gmk | ndk | MCA2975 | MCA2886 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.932 |