Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCA2985PAP2 superfamily protein; Identified by match to protein family HMM PF01569. (175 aa)    
Predicted Functional Partners:
MCA2984
Conserved hypothetical protein; Identified by similarity to OMNI:VC2487; match to protein family HMM TIGR00661.
 
     0.943
uppP
Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
  
 
 0.914
uppS
Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
    
 0.907
MCA1133
Putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase; Identified by similarity to SP:P24235; match to protein family HMM PF00953.
    
  0.900
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
    
  0.900
MCA2117
Rhodanese-like domain/ankyrin repeat domain protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
  
 
   0.562
MCA2986
Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106.
   
   0.561
cyp51
Cytochrome P450 51; Identified by similarity to SP:P77901; match to protein family HMM PF00067.
  
 0.548
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.545
MCA1569
Putative long-chain fatty-acid-CoA ligase; Identified by similarity to SP:P94547; match to protein family HMM PF00501.
    
 0.539
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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