Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA3012Conserved domain protein; Identified by similarity to GP:5738269. (314 aa)    
Predicted Functional Partners:
MCA3009
PHP N-terminal domain protein; Identified by match to protein family HMM PF02231.
     
 0.779
MCA3010
Conserved hypothetical protein; Identified by similarity to GP:19916313; match to protein family HMM PF04326.
       0.775
MCA3011
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SM00499.
       0.773
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.766
MCA3007
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SS00950.
     
 0.761
MCA3006
Transcriptional regulator, AbrB family; Identified by match to protein family HMM TIGR01439.
       0.757
MCA3008
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SM00500; match to protein family HMM PF06634.
       0.757
MCA3005
ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by similarity to OMNI:NTL01SM00503; match to protein family HMM PF00176; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851.
       0.621
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
    
 
 0.530
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.