node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCA2098 | dnaE | MCA2098 | MCA1286 | Putative DNA polymerase III, chi subunit; Identified by similarity to SP:P28905; match to protein family HMM PF04364. | DNA polymerase III, alpha subunit; Identified by similarity to SP:P10443; match to protein family HMM PF01336; match to protein family HMM PF02231; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | 0.979 |
MCA2098 | dnaN | MCA2098 | MCA3032 | Putative DNA polymerase III, chi subunit; Identified by similarity to SP:P28905; match to protein family HMM PF04364. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.971 |
MCA2098 | dnaQ | MCA2098 | MCA0720 | Putative DNA polymerase III, chi subunit; Identified by similarity to SP:P28905; match to protein family HMM PF04364. | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.931 |
MCA2098 | dnaZX | MCA2098 | MCA1328 | Putative DNA polymerase III, chi subunit; Identified by similarity to SP:P28905; match to protein family HMM PF04364. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.982 |
MCA2098 | holA | MCA2098 | MCA1451 | Putative DNA polymerase III, chi subunit; Identified by similarity to SP:P28905; match to protein family HMM PF04364. | DNA polymerase III, delta subunit; Identified by similarity to SP:P28630; match to protein family HMM PF06144; match to protein family HMM TIGR01128. | 0.992 |
MCA2098 | holB | MCA2098 | MCA1995 | Putative DNA polymerase III, chi subunit; Identified by similarity to SP:P28905; match to protein family HMM PF04364. | DNA polymerase III, delta prime subunit; Identified by similarity to SP:P28631; match to protein family HMM TIGR00678. | 0.985 |
MCA2098 | polI | MCA2098 | MCA2573 | Putative DNA polymerase III, chi subunit; Identified by similarity to SP:P28905; match to protein family HMM PF04364. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.404 |
MCA2522 | dnaA | MCA2522 | MCA3033 | DnaA domain protein; Identified by similarity to OMNI:NTL03PA00948; Belongs to the DnaA family. HdA subfamily. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.500 |
MCA2522 | dnaN | MCA2522 | MCA3032 | DnaA domain protein; Identified by similarity to OMNI:NTL03PA00948; Belongs to the DnaA family. HdA subfamily. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.966 |
MCA2522 | polI | MCA2522 | MCA2573 | DnaA domain protein; Identified by similarity to OMNI:NTL03PA00948; Belongs to the DnaA family. HdA subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.481 |
MCA2522 | recF | MCA2522 | MCA3031 | DnaA domain protein; Identified by similarity to OMNI:NTL03PA00948; Belongs to the DnaA family. HdA subfamily. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.602 |
dnaA | MCA2522 | MCA3033 | MCA2522 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DnaA domain protein; Identified by similarity to OMNI:NTL03PA00948; Belongs to the DnaA family. HdA subfamily. | 0.500 |
dnaA | dnaN | MCA3033 | MCA3032 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.992 |
dnaA | recF | MCA3033 | MCA3031 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.928 |
dnaE | MCA2098 | MCA1286 | MCA2098 | DNA polymerase III, alpha subunit; Identified by similarity to SP:P10443; match to protein family HMM PF01336; match to protein family HMM PF02231; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | Putative DNA polymerase III, chi subunit; Identified by similarity to SP:P28905; match to protein family HMM PF04364. | 0.979 |
dnaE | dnaN | MCA1286 | MCA3032 | DNA polymerase III, alpha subunit; Identified by similarity to SP:P10443; match to protein family HMM PF01336; match to protein family HMM PF02231; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.983 |
dnaE | dnaQ | MCA1286 | MCA0720 | DNA polymerase III, alpha subunit; Identified by similarity to SP:P10443; match to protein family HMM PF01336; match to protein family HMM PF02231; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.980 |
dnaE | dnaZX | MCA1286 | MCA1328 | DNA polymerase III, alpha subunit; Identified by similarity to SP:P10443; match to protein family HMM PF01336; match to protein family HMM PF02231; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.983 |
dnaE | holA | MCA1286 | MCA1451 | DNA polymerase III, alpha subunit; Identified by similarity to SP:P10443; match to protein family HMM PF01336; match to protein family HMM PF02231; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | DNA polymerase III, delta subunit; Identified by similarity to SP:P28630; match to protein family HMM PF06144; match to protein family HMM TIGR01128. | 0.981 |
dnaE | holB | MCA1286 | MCA1995 | DNA polymerase III, alpha subunit; Identified by similarity to SP:P10443; match to protein family HMM PF01336; match to protein family HMM PF02231; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | DNA polymerase III, delta prime subunit; Identified by similarity to SP:P28631; match to protein family HMM TIGR00678. | 0.983 |